What Is Erythema Multiforme?

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By james
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1. Signs and Symptoms of Erythema Multiforme

Usually, the primary indicator of erythema multiforme is the abrupt appearance of a characteristic rash. However, depending on the severity of the condition, other symptoms can precede skin manifestations. Erythema multiforme is usually symmetrical and it frequently appears first in the extremities (feet or the backs of the hands) before spreading towards the center of the body (trunk, face, neck).

The lesions in mild erythema multiforme usually start as red spots that rapidly progress to concentric lesions that are shaped like a target. For instance, in the center of the initial lesion, a small vesicle or “bump “develops. Then, a raised and pale ring appears, surrounding the previous lesion. Finally, its borders become purple or dark; thus, forming two concentric rings around the center.

Erythema Multiforme

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